Cat #: 08-013
PolyPlus-transfection 101000173 LipidBrick® IM21.7c, Cationic Lipid For LNP Formulation, 250mg/Unit
Cat #: 08-013
PolyPlus-transfection 101000173 LipidBrick® IM21.7c, Cationic Lipid For LNP Formulation, 250mg/Unit
Cationic Lipid For LNP Formulation
250mg/Unit
Brand: Polyplus-transfection- Efficiently modulate LNP properties to tailor biodistribution to the therapeutic purpose
- Secure by using a unique lipid structure protected by an independent patent owned by Polyplus®
- In vitro and in vivo proof of concept have been successfully performed
$1,276.80
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Cationic Lipid For LNP Formulation
250mg/Unit
Brand: Polyplus-transfection- Efficiently modulate LNP properties to tailor biodistribution to the therapeutic purpose
- Secure by using a unique lipid structure protected by an independent patent owned by Polyplus®
- In vitro and in vivo proof of concept have been successfully performed
LipidBrick® IM21.7c is a novel cationic lipid dedicated to the formulation of lipid nanoparticles (LNPs) for the development of mRNA-based vaccines and therapeutics. LipidBrick® IM21.7c overcomes the challenges proposed by the current generation of ionisable lipids used in LNPs, allowing for wider in vivo biodistribution and reduced accumulation in the liver. Proof-of-concept work has demonstrated that the intrinisc properties of LipidBrick® IM21.7c in modulating the overall electrical charge of LNPs extend the in vivo biodistribution and improve both drug efficacy and formulation stability without inducing safety concerns.
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